Retinol vs Bakuchiol: What No One Tells You

Is bakuchiol truly the gentler, natural answer to retinol? Or are its benefits overhyped?

After struggling with the harsh effects of retinol for years, I found my answer in bakuchiol—and it transformed my skin.

I've written extensively about the skincare ingredient bakuchiol, and I've also discussed the main reasons people quit retinoids. However, there's no question that retinoids are highly effective, so now it's time to pit the two ingredients head-to-head in this article that will definitively compare bakuchiol vs retinol.

If you've decided you cannot (or will not) use retinoids, you've probably been scouring Sephora's shelves for an effective bakuchiol serum. Wrinkles and acne can be stamped out with different strategies and ingredients. Bakuchiol is the popular choice, and there's good reason why.

But in the fight between bakuchiol vs retinol, what comes out ahead?

What’s the Difference Between Bakuchiol and Retinol?

Clearly, I'm biased. I love bakuchiol, and I'm the founder of a skincare brand that sells an award-winning bakuchiol serum.

There are many differences between bakuchiol and retinol. In order to provide as balanced and unbiased a review as possible, I decided to ask AI for an unbiased summary comparing the two ingredients. Then I declared a winner in each category:

• Ingredient Source: Bakuchiol is natural, derived from the Psoralea corylifolia plant. Retinoids are synthetic or derived from Vitamin A. This is a tie. Preference depends on how much natural sourcing matters to you.

• Skin Irritation: Retinoids cause skin irritation, redness, and peeling, especially when you first start using them or if you use them in higher concentrations. Bakuchiol, on the other hand, does not cause irritation, making it a more gentle option for people with sensitive skin. Winner: Bakuchiol.

• Antioxidant Properties: Both have antioxidant benefits, but bakuchiol also has anti-inflammatory and antibacterial effects, making it ideal for acne-prone and sensitive skin. Winner: Bakuchiol.

• Mechanism of Action: Retinoids bind and activate retinoic acid receptors in skin, causing increased cell turnover and collagen production. Bakuchiol acts on similar receptors but works differently at the cellular level, making it gentler. Winner: ?

• Sun Sensitivity: Retinoids increase sun sensitivity, while bakuchiol does not. Winner: Bakuchiol.

• Eye Dryness: Eye involvement from meibomian gland dysfunction is a possible complication of using retinol. This has not been reported in bakuchiol users. Thankfully, the damage shouldn't be permanent, but you should always consult with a dermatologist before using retinoids if this has happened to you. Winner: Bakuchiol.

• Acne Worsening: Due to the changes in cell turnover, retinol may cause initial purging (worsening acne); bakuchiol does not. Winner: Bakuchiol.

• Pregnancy: Out of an abundance of caution, topical retinoids, particularly prescription retinoids like retinoic acid, are not recommended during pregnancy. Bakuchiol is a safer alternative during pregnancy. Winner: Bakuchiol.

• Compatibility with Other Skincare Ingredients: Some skincare ingredients, such as benzoyl peroxide, reduce the effectiveness of retinoids. It's not advisable to use retinol with Vitamin C or hydroxy acids. Bakuchiol doesn't have these same compatibility issues, making it a more versatile ingredient. Winner: Bakuchiol.

• Research and Proven Efficacy: Retinoids have been extensively studied and are proven to combat a variety of skin issues, from acne to signs of aging. While early research on bakuchiol is promising, and it appears to provide similar benefits to retinoids, there's still less scientific evidence supporting its use, mainly because it's a newer ingredient. Retinol & bakuchiol tie, BUT the entire class "retinoid" wins overall.

• Availability and Cost: Retinoids come in both over-the-counter versions (like retinol) and stronger, prescription-strength versions. Bakuchiol, being a natural compound, is available over the counter. However, it is often more expensive as it is a niche product. Winner: Retinol.

Which One Should You Choose?

The current evidence comparing bakuchiol vs retinol head-to-head found bakuchiol to be comparable to retinol (this was at a 0.5% concentration for both ingredients).

This makes it safe to assume you will see results regardless of which ingredient you choose.

When it comes to chemical structure and function, bakuchiol is a meroterpene phenol. Even though the skin effects and visible results are comparable to retinol, the bakuchiol molecule is not similar. The two both work on cells that produce collagen and melanin. The end result is similar, but the chemical structures are unrelated. This explains why the two have such different side effects.

Everybody wants to know if bakuchiol is better than retinol.

The current evidence only suggests bakuchiol is comparable—not better. For some people, it's better (particularly people who can't or won't use retinol). 

Another issue is that there isn't any data comparing bakuchiol to prescription retinoids. When it comes to a long-term comparison of bakuchiol vs retinoids (not just retinol), the safe assumption is that retinoids (as a whole) are probably more effective. The data for retinoids goes back to at least 1984.

However, there are many other factors to consider when deciding what to use. Results matter, but not if the risks or side effects are too high. So many people can't tolerate retinol due to the skin barrier damage it causes. That is why we view retinol alternative regimens as important options.

Bakuchiol vs. Retinol FAQ 

1️⃣ How does bakuchiol compare to retinol?

Bakuchiol and retinol share many of the same benefits, including reducing fine lines, boosting collagen, and improving skin texture. However, bakuchiol is gentler, making it a great option for people who experience irritation with retinoids.

The key differences:

• • Retinol: Proven anti-aging benefits, but can cause redness, peeling, and sun sensitivity.
  • Bakuchiol: A plant-based alternative that offers similar effects without irritation or sun sensitivity.

2️⃣ Is bakuchiol better than retinol?

It depends on your skin type and goals.

• • If you tolerate retinol well, it’s backed by decades of research for anti-aging and acne.
  • If you have sensitive skin, experience irritation, or prefer plant-based ingredients, bakuchiol is the better choice.

For many people, retinoids simply aren’t an option due to redness, peeling, or pregnancy restrictions—this is where bakuchiol shines.

3️⃣ Does bakuchiol have side effects?

Bakuchiol is well-tolerated by most skin types, but like any skincare ingredient, it’s not completely risk-free. Some people may experience:

• • Mild irritation if introducing it too quickly.
  • Breakouts if paired with incompatible products.
  • Allergic reactions (rare but possible—always patch test first).

Unlike retinol, bakuchiol does not cause peeling, dryness, or sun sensitivity.

4️⃣ Can you use bakuchiol and retinol together?

Yes! Unlike some skincare ingredients that conflict, bakuchiol and retinol can actually complement each other.

✔ Bakuchiol may help reduce irritation from retinol by offering antioxidant and anti-inflammatory benefits.
✔ It can be used in the morning, while retinol is typically used at night.

However, if you have sensitive skin, start slow and monitor how your skin responds.

5️⃣ Is bakuchiol better than retinol for acne?

Retinol is a gold standard for acne treatment, helping to unclog pores and speed up cell turnover. However, it can also cause dryness, irritation, and purging—making it difficult for some people to tolerate.

Bakuchiol offers a gentler alternative that may still help acne-prone skin:
✔ Anti-inflammatory & antibacterial properties can help reduce breakouts.
✔ No purging period—it won’t trigger an initial flare-up.
✔ More compatible with sensitive skin that struggles with retinoids.

While bakuchiol isn’t a direct replacement for prescription-strength retinoids, it’s a great option for those who want acne support without irritation.

6️⃣ How long does it take to see results with bakuchiol?

Bakuchiol works gradually and, like retinol, requires consistency.

📆 4–6 weeks: Initial improvements in skin texture and hydration.
📆 8–12 weeks: Visible reduction in fine lines, wrinkles, and discoloration.
📆 3+ months: Continued benefits for anti-aging and acne prevention.

Since bakuchiol doesn’t cause irritation, you can typically use it daily from the start, unlike retinol, which requires a slow buildup.

7️⃣ Can Retinol or Bakuchiol Cause Eye Dryness?

Retinol is known to cause dryness and irritation, especially around the eyes and eyelids. This is because retinoids can disrupt the meibomian glands, which produce oils that keep your eyes lubricated. Some people experience dry eye syndrome or increased sensitivity after using retinol.

🔹 What About Bakuchiol?
Unlike retinol, bakuchiol does not cause eye dryness because it doesn’t affect oil production in the same way. If you have sensitive eyes or are prone to dryness, bakuchiol may be a better choice for targeting wrinkles and fine lines around the delicate eye area.